7th International Workshop on Breast Densitometry and
Cancer Risk Assessment (Non-CME)

We invite you to attend the 7th International Breast Densitometry and Breast Cancer Risk Assessment Workshop in San Francisco, June 10-12, 2015. A high amount of dense breast tissue has been shown to be one of the strongest risk factors for breast cancer, although the specific reason(s) for this is not known. Recent legislation in several states, including California, requires reporting of breast density to women with dense breasts undergoing mammography. Ideally, prior to enacting legislation, there would be guidelines on how best to measure breast density, what risk model to use that includes breast density to report breast cancer risk, as well as a standardized form to communicate this information. Research is ongoing to understand how different technologies that measure breast density relate to both breast cancer detection and breast cancer risk.

The 2015 Conference will feature three days of presentations consisting of approximately 15 internationally-recognized invited speakers, and 4 presentations selected from submitted abstracts. In addition, there will be a poster session both days to highlight research from attendees. All registered participants are encouraged to submit an abstract for either poster or oral presentation. All parts of this workshop are devoted to the breast cancer objectives.

Travel Scholarships for Advocates: Breast cancer advocates that submit abstracts will be considered for a travel scholarship.

The participants will leave the workshop having gained tangible understanding and insights to the clinical applications and research topics in breast density. Specifically, the participants will have a complete overview of the current trends, capabilities, and limitations of risk factors from mammographic imaging. Second, the participants will have a key understanding of how or if these imaging risk factors are independent from other clinical and genetic risk factors. Third, the participant will know the key needs and research breakthroughs needed to best identify women at high risk of breast cancer. These agenda topics are further described with the speakers associated with each topic in our specific program below.

Wednesday, June 10, 2015

7:30am Registration and Continental Breakfast

Clinical Aspects of Breast Density

8:30am Introduction
John Shepherd

8:40am Advocate Clinical Statement
Vivian Lee

8:50am Breast Density Methods in Clinical Practice
Jennifer Harvey

9:40am Breast Density and Other Risk Factors of Breast Cancer
Giske Ursin

10:30am Coffee Break

11:00am Identifying Women with Dense Breasts at High Risk of Interval Cancers
Karla Kerlikowske

11:50am Luncheon Symposium: Dense Breast Tissue: Risk of Breast Cancer and the
Limitations of Mammography ‐ Sponsored by GE Healthcare and Volpara
Susan Roux, MD

1:20pm Reporting – Guidelines and Experience from CBDIG
Debra M. Ikeda

2:10pm Non‐mammographic Screening Strategies and Emerging Technologies for High
Density Women
Wendie Berg

3:00pm Coffee Break

3:30pm Case Examples
Debra M. Ikeda &
Jennifer Harvey

4:30pm Panel Discussion

5:00pm Adjourn

5:00pm – 6:00pm Networking Reception

Thursday, June 11, 2015

8:00 am Continental Breakfast
Comparative Measures of Breast Density Moderator: Isabel Silva

8:30 am Advocates Introduction
Vivian Lee

8:40 am Masking Models and Breast Density
James Mainprize

9:15 am Comparative Automated Clinical Measures of Breast Density
Celine Vachon

9:50 am New Ultrasound Approaches for Identifying Women with High Breast Density and
Screening them for Breast Cancer
Neb Duric

10:25 am Coffee Break

11:00 am Multi‐Modality Breast Imaging Radiomics of Tumors and Parenchymal Density & Texture
Abstract Proffered Talk(s)
Maryellen Giger

11:35 am Fibroglandular tissue measured as mammographic density and texture
(amount and distribution) can individually and jointly contribute to breast cancer
risk assessment
Rikke Winkel

11:50 am Early growth and breast‐tissue composition at the end of breast development:
exploring the pathways to breast cancer risk in prepubertal girls
Ana Pereira

12:05 pm Lunch and Poster Session 1
Afternoon Program - Breast Density and Biology and Genetics: Moderator: Per Hall

1:30 pm Molecular Epidemiology and Biology of Mammographic Density in the BREAST
Stamp Project
Gretchen Gierach

2:05 pm Tissue Stiffness Can Contribute to Invasive Carcinoma
Ovijit Chaudhuri

2:40pm Coffee Break

3:10pm Genetics of Breast Density and Breast Cancer
Rulla Tamimi

3:45pm Adolescence and Breast Density
Abstract Proffered Talk(s)
Karin Michels

4:20 pm Mammographic density and breast cancer intrinsic subtypes
Laurel Habel

4:35 pm Functional assessment of breast fibroglandular tissue: correlations between
MBI and MRI
Carrie Hruska

4:50 pm Panel Discussion & Summary of Day One Moderators:
Karla Kerlikowske
John Shepherd

7:00 pm Group Dinner pre‐registration required

Friday, June 12, 2015

8:00am Continental Breakfast

Risk Modeling – Putting it All Together I - Moderator Celine Vachon

8:30 am Mammographic Density Pooling Project – Insights from an International Perspective
Valerie McCormack

9:05 am Benign Breast Disease, Mammographic Breast Density and Breast Cancer Risk
Jeff Tice

9:40 am Tyrer/Cuzick Model with Density
Jack Cuzick

10:15 am Coffee Break
Threshold Probabilities for Clinical Recommendations - Moderator Karla Kerlikowske

10:35 am Cost‐Effectiveness and Harm‐Benefit Analyses of Risk‐Based Screening Strategies
for Breast Cancer
Ester Vilaprinyo

11:10 am Quantifying the Net Benefit of Mammography Screening Intervals Based on Screening
Interval, Risk, Breast Density and Age
Abstract Proffered Talk(s) - Celine Vachon
Anna Tosteson

11:45 am Combined Effect of Dense and Nondense Breast Volume on Breast Cancer Risk
Johanna Wanders

12:00 pm Mammographic Density and breast cancer risk: A mediation analysis
Megan Rice

12:15 pm Lunch and Poster Session 2
Putting it All Together II Moderator – Karla Kerlikowske

1:45 pm Assessing breast cancer masking risk in full field digital mammography with
automated texture analysis
Mads Nielsen

2:00 pm Density, Dose, and Digital Breast Tomosynthesis
Ralph Hinghnam

2:15 pm Panel Discussion, Summary, and Closing
Moderators:
Karla Kerlikowske
John Shepherd

3:00 pm Adjourn

John Shepherd, PhD
Associate Professor of Radiology and Biomedical Imaging
University of California, San Francisco

Karla Kerlikowske, MD
Professor of Medicine
University of California, San Francisco

Steven R. Cummings, MD
Director, SF Coordinating Center
Sutter Health Cal-Pacific Medical Center
San Francisco, California

Scientific Advisory Committee

Norman F Boyd, DSc, MD, FRCPC
Professor in the Departments of Medicine,
Medical Biophysics and Nutritional Sciences, University of Toronto, Canada

Celine Vachon PhD
Professor of Epidemiology in the Division of Epidemiology,
Department of Health Sciences Research, Mayo Clinic, Rochester, MN

Isabel dos Santos Silva MD MSc PhD
Professor of Epidemiology, University of London, London, UK.
Per Hall MD PhD. Professor in the Medical Epidemiology and Biostatistics
Department at the Karolinska Institute, Stockholm Sweden.

Wendie Berg

Norman Boyd

Ovijit Chaudhuri

Jack Cuzick

Kamila Czene

Neb Duric

Gretchen Gerlach

Mary Ellen Giger

Jennifer Harvey

Debra Ikeda

Vivian Lee

James Mainprize

Valerie McCormack

Karin Michels

RullaTamimi

Jeff Tice

Anna Tosteson

Celine Vachon

Ester Vilaprinyo

Hotel Kabuki
1625 Post St
San Francisco, CA 94115
415-922-3200

Hotel Rates: $209/night
Cutoff: 5/9/15 or until room block is filled
Reservations: 800-533-4567
Group ID: 06097THI